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. 2016 Oct 7;234(9):1499–1510. doi: 10.1007/s00213-016-4453-0

Table 1.

Statistics for the effects of LSD in the 5D-ASC and MEQ

LSD 100 μg
T test vs. placebo
LSD 200 μg
T test vs. placebo
LSD 100 vs. 200 μg
T test
T= P= T= P= T= P=
5 Dimensions Altered States of Consciousness (ASC) scale
 Total ASC score 9.72 <0.001 10.02 <0.001 2.23 <0.05
 Oceanic boundlessness 8.44 <0.001 9.61 <0.001 1.89 NS
 Anxious ego dissolution 6.43 <0.001 4.01 <0.001 1.50 NS
 Visionary restructuralization 9.79 <0.001 15.32 <0.001 2.34 <0.05
 Auditory alterations 3.72 <0.01 5.87 <0.001 0.42 NS
 Reductions of vigilance 7.44 <0.001 5.93 <0.001 0.79 NS
 Experience of unity 6.85 <0.001 7.77 <0.001 0.68 NS
 Spiritual experience 4.31 <0.001 3.91 <0.001 1.10 NS
 Blissful state 6.56 <0.001 8.27 <0.001 3.00 <0.01
 Insightfulness 4.11 <0.001 5.81 <0.001 2.28 <0.05
 Disembodiment 6.93 <0.001 5.87 <0.001 0.13 NS
 Impaired control and cognition 7.01 <0.001 5.04 <0.001 0.86 NS
 Anxiety 3.02 <0.001 2.04 NS 1.37 NS
 Complex imagery 7.10 <0.001 7.48 <0.001 0.31 NS
 Elementary imagery 9.96 <0.001 11.12 <0.001 0.57 NS
 Audio-visual synsthesia 9.19 <0.001 12.52 <0.001 1.96 NS
 Changed meaning of percepts 6.25 <0.001 9.66 <0.001 3.39 <0.01
 Ego dissolution (item 71) 7.63 <0.001 5.32 <0.001 0.36 NS
Mystical Effects Questionnaire (MEC43)
 Internal unity NA NA 6.22 <0.001 NA NA
 External unity NA NA 6.08 <0.001 NA NA
 Sacredness NA NA 6.80 <0.001 NA NA
 Noetic quality NA NA 5.71 <0.001 NA NA
 Deeply felt positive mood NA NA 11.43 <0.001 NA NA
 Transcendence of time/space NA NA 10.63 <0.001 NA NA
 Ineffability NA NA 16.22 <0.001 NA NA
Mystical Effects Questionnaire (MEQ30)
 Mystical NA NA 5.99 <0.001 NA NA
 Positive mood NA NA 13.13 <0.001 NA NA
 Transcendence of time/space NA NA 11.12 <0.001 NA NA
 Ineffability NA NA 25.14 <0.001 NA NA
 MEC30 total score NA NA 14.91 <0.001 NA NA

Sixteen subjects participated in the high-dose study (200 μg) and 24 subjects in the moderate-dose study (100 μg). Dependent T tests were performed to assess differences from placebo, and independent T tests were performed to assess differences between doses of LSD

NA not assessed