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. 2017 May 6;14:100. doi: 10.1186/s12974-017-0873-y

Fig. 4.

Fig. 4

DRα1-mMOG-35-55 treatment efficacy of chronic EAE in female mice depends on sex hormones. Mean EAE daily scores of OVX female C6 mice at a clinical/6 mice treated with 100 μg DRα1-mMOG-35-55 or vehicle (injection days indicated by black arrows) (left) and cumulative disease index scores (right) are shown. *p ≤ 0.05. Daily mean scores were analyzed by Mann-Whitney U and mean CDI by Student’s t test