Table 1.

IC₅₀ of the extraction and fractions from A. iwayomogi on aldose reductase (AR) and advanced glycation endproducts (AGEs) formation.

Sample	IC50a (μg/ml)
	AR	AGEs formation
50% EtOH ext.	2.71 ± 0.72∗∗	40.99 ± 0.50∗
CHCl3 fr.	15.36 ± 3.64∗∗	7.29 ± 0.05∗
30% MeOH fr.	1.16 ± 0.10∗	40.81 ± 0.05∗
60% MeOH fr.	1.42 ± 0.17∗	93.76 ± 0.06∗
100% MeOH fr.	0.79 ± 0.15∗	38.40 ± 0.51∗
Water fr.	19.67 ± 0.81∗∗	402.45 ± 4.28∗∗
TMGb	1.22 ± 0.03∗	—
AGc	—	45.85 ± 7.17∗∗

^aIC₅₀ calculated from the least-squares regression line of the logarithmic concentrations plotted against the residual activity.

^cTMG was used as a positive control.

^cAG was used as a positive control.

^∗Significant difference from control; ^∗p < 0.05, ^∗∗p < 0.01.