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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Am J Obstet Gynecol. 2016 Dec 30;216(5):527.e1–527.e9. doi: 10.1016/j.ajog.2016.12.174

Figure 1.

Figure 1

Predicted plasma inflammation biomarker concentrations and 95% confidence intervals by gestational age at sample collection in preeclamptic (red) vs. normotensive (gray) pregnancies.

Predicted values from generalized additive mixed models of ln-transformed inflammation biomarker concentrations in relation to Loess-smoothed gestational age at sample collection with an interaction term for preeclampsia. Models include a random intercept for subject ID and are weighted for generalizability to the base cohort population. Solid lines represent predicted values and dashed lines represent lower and upper 95% confidence limits for each group. Points represent actual biomarker concentrations measured in mothers who developed preeclampsia (red) vs. mothers who had normotensive pregnancies (black).