Table 3.
Tests for Association Between Genotype and Response to Sertraline. Linear Regression Models
Gene | ELC | RLRS | ELRS | VRRS | FMRS | VRAES | FMAES | CTS | SPRS | CGI-I |
---|---|---|---|---|---|---|---|---|---|---|
Tests | ||||||||||
Serotonin | 0.48 | 0.345 | 0.469 | 0.4 | 0.912 | 0.331 | 0.906 | 0.356 | 0.057 | 0.135 |
BDNF | 0.015 | 0.257 | 0.729 | 0.234 | 0.965 | 0.165 | 0.796 | 0.017 | 0.239 | 0.008 |
MAOA | 0.591 | 0.438 | 0.724 | 0.099 | 0.215 | 0.127 | 0.31 | 0.518 | 0.086 | 0.085 |
2C19 | 0.881 | 0.966 | 0.706 | 0.439 | 0.102 | 0.545 | 0.181 | 0.905 | 0.524 | 0.018 |
2D6 | 0.189 | 0.533 | 0.526 | 0.895 | 0.8 | 0.86 | 0.629 | 0.256 | 0.07 | 0.619 |
Adjusting for category, gender, and baseline score
ELC, Receptive Language Raw Score (RLRS), Expressive Language Raw Score (ELRS), Visual Reception Raw Score (VRRS), Fine Motor Raw Score (FMRS), Visual Reception Age Equivalent Score (VRAES), Fine Motor Age Equivalent Score (FMAES), Cognitive T Score (CTS), Social Participation Raw Score (SPRS) and Clinical Global Impression Improvement (CGI-I).