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. Author manuscript; available in PMC: 2018 Feb 7.
Published in final edited form as: AIDS. 2017 Jan 14;31(2):233–240. doi: 10.1097/QAD.0000000000001327

Table 4.

Characteristics of VIA/Pap/HR-HPV testing for post-treatment follow-up for detection of CIN2+.a

Sensitivity Specificity Correctly Classified PPV NPV
VIA 0.27 (0.18, 0.36) 0.82 (0.79, 0.86) 0.72 (0.68, 0.77) 0.25 (0.17, 0.33) 0.84 (0.80, 0.88)
PAP 0.44 (0.35, 0.53) 0.91 (0.88, 0.95) 0.83 (0.79, 0.87) 0.52 (0.42, 0.62) 0.88 (0.84, 0.92)
HR HPV 0.85 (0.75, 0.96) 0.54 (0.49, 0.58) 0.59 (0.55, 0.64) 0.29 (0.23, 0.34) 0.94 (0.90, 0.99)
VIA & PAP 0.13 (0.08, 0.17) 0.97 (0.95, 0.99) 0.82 (0.78, 0.86) 0.50 (0.32, 0.68) 0.84 (0.80, 0.87)
VIA & HR HPV 0.22 (0.15, 0.29) 0.89 (0.86, 0.93) 0.77 (0.74, 0.81) 0.31 (0.21, 0.41) 0.84 (0.80, 0.88)
PAP & HR HPV 0.31 (0.24, 0.38) 0.94 (0.92, 0.97) 0.83 (0.79, 0.86) 0.54 (0.44, 0.65) 0.86 (0.83, 0.90)
VIA & PAP & HR HPV 0.09 (0.05, 0.13) 0.98 (0.96, 0.99) 0.82 (0.78, 0.86) 0.45 (0.26, 0.65) 0.83 (0.79, 0.87)
VIA | PAP 0.59 (0.48, 0.69) 0.76 (0.72, 0.81) 0.73 (0.69, 0.77) 0.35 (0.28, 0.41) 0.89 (0.85, 0.94)
VIA | HR HPV 0.90 (0.80, 1.00) 0.47 (0.42, 0.51) 0.54 (0.50, 0.59) 0.27 (0.22, 0.32) 0.96 (0.90, 1.00)
PAP | HR HPV 0.99 (0.89, 1.00) 0.51 (0.46, 0.55) 0.59 (0.55, 0.64) 0.30 (0.25, 0.35) 0.99 (0.95, 1.00)
VIA | PAP | HR HPV 1.00 (0.91, 1.00) 0.44 (0.39, 0.48) 0.54 (0.49, 0.58) 0.28 (0.23, 0.32) 1.00 (1.00, 1.00)
a

Analysis assumed triple negatives are truly negatives and imputed those with otherwise missing histology