BAG4, IL6ST, VWF, EGFR, and CD44 levels were examined in plasma from people with villous adenoma, carcinoma-in-situ, or invasive cancer cases compared to controls (collected prior to colonoscopy). Albumin and IgG depleted plasma proteins (30 µg) were separated on a denaturing 4–12% Bis-Tris gel under reducing conditions. After immunoblot and primary antibody incubation, specific bands were visualized with a fluorescently-labeled secondary antibody. Statistical significance: *, p<0.05; **, p<0.01; ***, p<0.001; ****, p<0.0001.