Table IV.
Oxidative stress-related parameters and cardiac biomarkers
| Parameter | Plasma ascorbate [mmol/l] | FRAP [μmol/l] | GSH [mmol/l] | CKMB [U/l] | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asc | Placebo | P-value | Asc | Placebo | P-value | Asc | Placebo | P-value | Asc | Placebo | P-value | |
| N | 15 | 25 | 15 | 25 | 15 | 25 | 15 | 25 | ||||
| M1 | 0.04 (0.02–0.09) | 0.02 (0.01–0.05) | 0.9674 | 271.7 (200.2–396.4) | 304.1 (213.0–429.6) | 0.3043 | 4.11 (3.61–6.56) | 3.59 (3.21–4.54) | 0.7714 | 41.00 (22.40–98.00) | 33.00 (24.00–69.00) | 0.4092 |
| M2 | 9.63 (6.25–11.64) | 0.02 (0.01–0.03) | < 0.0001 | 8050.0 (50275.0–11418.0) | 310.3 (227.7–400.0) | < 0.0001 | 3.71 (1.75–4.60) | 3.92 (3.26–5.28) | 0.0149 | – | – | |
| M3 | 0.72 (0.23–2.43) | 0.02 (0.01–0.04) | < 0.0001 | 1080.0 (699.9–2062.0) | 287.5 (250.2–391.2) | < 0.0001 | 2.59 (1.61–4.15) | 4.13 (3.48–5.06) | 0.0198 | 335.50 (134.00–478.30) | 387.00 (189.00–725.00) | 0.6642 |
| M4 | 0.02 (0.01–0.05) | 0.03 (0.01–0.05) | 0.8023 | 378.2 (257.9–464.3) | 352.2 (220.0–371.8) | 0.3568 | 3.87 (3.55–4.86) | 4.02 (3.34–4.43) | 0.7512 | – | – | |
Values are expressed as median (interquartile range). M1 – basal blood sample, M2 – immediately after reperfusion, M3 – 6 to 8 h after balloon deflation, M4 – at hospital discharge, Asc – ascorbate group, FRAP – ferric reducing ability of plasma, GSH – reduced glutathione, CKMB – creatine kinase MB.