Table III.
Results of follow-up surgical excision of LN diagnosed on core-needle biopsy: literature review and current study
| Study | Ref. | N | ALH | LCIS | LN | No. of upgrades (%) | Risk factors for upgrading |
|---|---|---|---|---|---|---|---|
| Middleton (2003) | [22] | 17 | 6 | 9 | 2 | 6 (35.3) | Mass lesion |
| Arpino (2004) | [16] | 21 | NA | NA | 21 | 3 (14.3) | – |
| Elsheikh & Silverman (2005) | [32] | 33 | 20 | 13 | NA | 9 (27.3) | Mass lesion, pleomorphic histology |
| Renshaw (2006) | [13] | 92 | 40 | 52 | NA | 3 (3.26) | – |
| Esserman (2007) | [18] | 26 | NA | NA | 26 | 2 (7.69) | Diffuse LCISb |
| Ciangiarella (2008) | [20] | 38 | 18 | 20 | NA | 3 (7.89) | Mass lesion |
| Hwang (2008) | [36] | 87 | 48 | 39 | NA | 10 (11.5) | Imaging-histologic discordance, pleomorphic histology |
| Menon (2008) | [34] | 25 | NA | NA | 25a | 9 (36.0) | Mass lesion, imaging-histologic discordance |
| Nagi (2008) | [35] | 45 | NA | NA | 45 | 2 (4.44) | – |
| Polom (2009) | [10] | 20 | 11 | 9 | NA | 8 (40.0) | Mass lesion, architectural distortion on mammography |
| Flegg (2010) | [11] | 9 | 4 | 5 | NA | 2 (22.2) | – |
| Rendi (2012) | [24] | 68 | 20 | 48 | NA | 3 (4.41) | Imaging-histologic discordance, women at high risk, extensive LCISc |
| Murray (2013) | [19] | 80 | 34 | 46a | NA | 5 (6.25) | Imaging-histologic discordance |
| Current study | 27 | NA | 27 | NA | 8 (29.6) | Mass lesion, BIRADS category 5, pleomorphic histology, palpability | |
| Total | 588 | 201 | 268 | 119 | 73 (12.4) | – |
NA – not applicable;
a
classic type,
b
> 1 lobule per core;
c
> 4 foci.