Table 2. Multivariate Cox regression analysis of the association between features of the patients and overall survival.

	Multivariate Cox analysis
Variables	HR	95% CI	P-value
Sex (female vs male)	0.348	0.095–1.282	0.113
Age (per year)	0.930	0.846–1.023	0.137
Tumor size	0.986	0.967–1.005	0.149
Location
Temporal vs frontal	0.669	0.173–2.588	0.560
Parietal vs frontal	0.085	0.007–1.001	0.050
Occipital vs frontal	1.030	0.061–17.460	0.984
Others vs frontal	1.500	0.097–23.118	0.771
Treatment
Surgery+RT vs Surgery	0.176	0.009–3.474	0.254
Surgery+RT+CTx vs Surgery	0.009	0.000–0.223	0.004a
Surgery+RT+CTx+GKS vs Surgery	0.002	0.000–0.071	0.001a
TP53 (mutated vs non-mutated)	23.933	2.869–199.634	0.003a

Abbreviations: CI, confidence interval; CTx, chemotherapy; GKS, gamma knife surgery; HR, hazard ratio; RT, radiotherapy.

^aIndicate significance at P<0.05.