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. 2017 Apr 26;2(4):104–109. doi: 10.1302/2058-5241.2.160023

Table 1.

Criteria of Musculoskeletal Infection Society (MSIS) for retaining the prosthesis in periprosthetic infection26

There is a sinus tract communicating with the prosthesis; or
A pathogen is isolated by culture from at least two separate tissue or fluid samples obtained from the affected prosthetic joint; or
Four of the following criteria exist:

  1. Elevated serum erythrocyte sedimentation rate and serum C-reactive protein concentration,

  2. Elevated synovial leukocyte count,

  3. Elevated synovial neutrophil percentage,

  4. Presence of pus in the affected joint,

  5. Isolation of a micro-organism in one culture of periprosthetic tissue or fluid, or

  6. Greater than five neutrophils per high-power field in five high-power fields observed from histological analysis of peri-prosthetic tissue at ×400 magnification.