Table 1.
Comparison of retinal vessel parameters and SFCT between CADASIL patients and healthy controls
| Vessel parameters | CADASIL (n = 27) | Control (n = 27) | t | P |
|---|---|---|---|---|
| SFCT (µm) | 268.37 ± 46.50* | 300.53 ± 39.31 | −3.401 | <0.001 |
| Arteries (µm) | ||||
| Inner diameter | 93.46 ± 9.70* | 96.94 ± 8.28 | −2.068 | 0.048 |
| Outer diameter | 131.74 ± 10.87* | 127.36 ± 8.67 | 2.224 | 0.023 |
| Vessel wall | 19.13 ± 1.85* | 15.21 ± 1.47 | 12.367 | <0.001 |
| Veins (µm) | ||||
| Inner diameter | 128.99 ± 13.62† | 121.97 ± 11.29 | 2.737 | 0.004 |
| Outer diameter | 164.82 ± 14.77† | 149.60 ± 11.96 | 5.414 | <0.001 |
| Vessel wall | 17.91 ± 2.76† | 13.81 ± 1.47 | 9.656 | <0.001 |
| AVR | ||||
| AVRin | 0.72 ± 0.08† | 0.79 ± 0.07 | −5.718 | <0.001 |
| AVRout | 0.80 ± 0.06† | 0.85 ± 0.06 | −4.904 | <0.001 |
Data are presented as mean ± SD. *Means the SFCT and arterial parameters in CADASIL patients (n = 54) versus control (n = 54); †Means the venous parameters and AVR data in CADASIL patients (n = 51) versus control (n = 51); Three veins were excluded in CADASIL group due to questionable border discrimination of vessel walls; Paired t-test was used to analyze the date of normal distribution. SFCT: Subfoveal choroidal thickness; CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; AVRin: Arterial venous ratio of inner diameter; AVRout: Arterial venous ratio of outer diameter; SD: Standard deviation.