Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 17;198(10):4012–4024. doi: 10.4049/jimmunol.1601877

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 by The American Association of Immunologists, Inc.

This article is distributed under The American Association of Immunologists, Inc., Reuse Terms and Conditions for Author Choice articles.

PMC Copyright notice

FIGURE 4. — Stimulation of hPBMCs with TLR agonists and RNA. IFN-related (A) and proinflammatory (B) cytokines induced after stimulation were measured using the mesoscale discovery platform. Each column represents the mean with SEM from six donors. IFN-α (C) in hPBMCs and IFN-α (D) in pDCs were evaluated as in (A) in the presence of methylated ssRNA. Each column represents the mean with SEM from two donors. Splenocytes from TLR7^rsq1 (E), MyD88 KO (F), and TLR3 KO (G) were stimulated with the indicated TLR agonist or RNA, and IL-6 cytokines levels were measured 24 h later. Each column represents the mean with SEM from two different mice.