Table 2.
Risk of heart failure or heart failure and death among patients with community acquired pneumonia and controls. Values are numbers (percentages) unless stated otherwise
| Analyses | Controls (n=23 060) | Patients with pneumonia (n=4988) | Adjusted hazard ratio (95% CI) | P value |
|---|---|---|---|---|
| Primary analysis | ||||
| Incident heart failure: | ||||
| Combined endpoint | 1712 (7.4) | 592 (11.9) | 1.61 (1.44 to 1.81) | <0.001 |
| Inpatients | 875 (11.0) | 334 (18.3) | 1.94 (1.64 to 2.29) | <0.001 |
| Outpatients | 837 (5.6) | 258 (8.2) | 1.33 (1.12 to 1.57) | <0.001 |
| Secondary analyses | ||||
| Incident heart failure within 90 days: | ||||
| Combined endpoint | 145 (0.6) | 68 (1.4) | 1.52 (1.08 to 2.13) | <0.001 |
| Inpatients | 80 (1.0) | 41 (2.3) | 1.45 (0.90 to 2.34) | 0.1 |
| Outpatients | 65 (0.4) | 27 (0.9) | 1.38 (0.79 to 2.39) | 0.3 |
| Incident heart failure within 1 year: | ||||
| Combined endpoint | 321 (1.4) | 164 (3.3) | 1.86 (1.50 to 2.32) | <0.001 |
| Inpatients | 181 (2.3) | 106 (5.8) | 1.96 (1.46 to 2.64) | <0.001 |
| Outpatients | 140 (0.9) | 58 (1.8) | 1.54 (1.08 to 2.20) | 0.019 |
| Incident heart failure or all cause mortality: | ||||
| Combined endpoint | 6041 (26.2) | 2035 (40.8) | 1.53 (1.44 to 1.63) | <0.001 |
| Inpatients | 3172 (39.8) | 1178 (64.5) | 1.77 (1.62 to 1.93) | <0.001 |
| Outpatients | 2869 (19.0) | 857 (27.1) | 1.34 (1.23 to 1.47) | <0.001 |