Fig. 4.

Synthesis of the LLO analogs used in this study. (A) Synthesis of Chitobiose phosphate precursor (5). (B) Synthesis of lipid phosphate precursors (16a–d). (C) Coupling reaction and deacetylation of monophosphates 16a–d and 5 to final pyrophosphates 1a–d. Synthetic pathway is shown for 1c, yields and precursor names for the synthesis of 1a, 1b and 1d are shown in parentheses. This figure is available in black and white in print and in color at Glycobiology online.