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Kinetic parameters for the different synthetic LLO analogs and inhibitors
| LLO analog | KM (µM) | kcat(pep/min) |
|---|---|---|
| (1a) Citronellyl-PP-chitobiose | 95 ± 18 | 9.1 ± 0.5 |
| (1b) Farnesyl-PP-chitobiose | 5.6 ± 0.8 | 12 ± 1 |
| (1c) NerylCitronellyl-PP-chitobiose | 5.3 ± 0.9 | 23 ± 1 |
| (1d) FarnesylCitronellyl-PP-chitobiose | 2.5 ± 0.3 | 16 ± 1 |
| Inhibitory LLO | IC50 (µM) | |
| (34b) Farnesyl-PP-C-chitobiose | 167 ± 14 | |
| (34d) FarnesylCitronellyl-PP-C-chitobiose | 26 ± 3 | |
