Table 1.
Obstructive Coronary Disease | p Value | ||
---|---|---|---|
Yes (n = 176) | No (n = 194) | ||
Medical History | |||
Age (years) | 63 ± 14 | 57 ± 16 | < 0.001 |
Male gender | 121 (69%) | 90 (46%) | < 0.001 |
Body mass index (kg/m2) | 28 ± 4.8 | 28 ± 5.9 | 0.61 |
History of CAD | 68 (39%) | 55 (28%) | 0.03 |
Diabetes | 62 (36%) | 51 (26%) | 0.05 |
Hypertension | 122 (70%) | 138 (71%) | 0.83 |
Current smoking | 22 (13%) | 18 (9.3%) | 0.30 |
LDL cholesterol (mg/dL) | 113 ± 64 | 116 ± 87 | 0.72 |
Family history of CAD | 48 (28%) | 42 (22%) | 0.19 |
Chronic renal disease | 9 (5.3%) | 7 (3.6%) | 0.45 |
Plasma creatinine (mg/dL) | 0.95 (0.80 - 1.20) | 0.80 (0.70 - 1.15) | 0.10 |
Current statin therapy | 85 (49%) | 91 (47%) | 0.71 |
Current aspirin therapy | 75 (43%) | 76 (39%) | 0.44 |
Chest Pain Characteristics | |||
Left side location | 137 (79%) | 156 (81%) | 0.70 |
Oppressive nature | 97 (57%) | 95 (49%) | 0.14 |
Irradiation to neck | 39 (23%) | 51 (26%) | 0.42 |
Irradiation to left arm | 57 (33%) | 53 (27%) | 0.24 |
Vagal symptoms | 61 (36%) | 78 (40%) | 0.35 |
Number of episodes | 1 (1 - 2) | 1 (1 - 3) | 0.81 |
Duration (minutes) | 40 (15 - 120) | 40 (10 - 150) | 0.82 |
Intensity (1 - 10 scale) | 7.4 ± 2.5 | 7.1 ± 2.6 | 0.31 |
Relief with nitrate | 84 (50%) | 72 (37%) | 0.02 |
Similar to previous infarction | 70 (42%) | 63 (33%) | 0.08 |
Worsening with compression | 7 (4.1%) | 26 (13%) | 0.002 |
Worsening with position | 24 (14%) | 36 (19%) | 0.23 |
Worsening with arm movement | 7 (4.0%) | 16 (8.2%) | 0.097 |
Worsening with deep breath | 13 (7.5%) | 36 (19%) | 0.002 |
Laboratory Tests at Admission | |||
Ischemic changes on ECG | 120 (68%) | 73 (38%) | < 0.001 |
Positive troponin | 116 (66%) | 60 (31%) | < 0.001 |
X-ray and clinical signs of LVF | 26 (15%) | 5 (2.6%) | < 0.001 |
NT-proBNP (pg/mL) | 363 (105 - 1850) | 57 (20 - 235) | < 0.001 |
Plasma glucose (mg/dL) | 120 (97 - 189) | 112 (92 - 145) | 0.22 |
C-reactive protein (mg/L) | 7.3 (2.3 - 15) | 5.7 (1.4 - 15) | 0.09 |
White cell count | 8.790 ± 4.300 | 7.701 ± 2.865 | 0.004 |
Hemoglobin (g/dL) | 14.1 ± 1.9 | 13.7 ± 1.7 | 0.06 |
CAD: coronary artery disease; LVF: left ventricular failure. A family history of CAD implies in the presentation of the disease in a first-degree relative before the age of 55 years (females) or 45 years (males).