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. 2017 Apr;108(4):304–314. doi: 10.5935/abc.20170037

Table 1.

Comparison of medical history, chest pain characteristics, and laboratory tests between patients with and without obstructive coronary artery disease

  Obstructive Coronary Disease p Value
  Yes (n = 176) No (n = 194)  
Medical History
Age (years) 63 ± 14 57 ± 16 < 0.001
Male gender 121 (69%) 90 (46%) < 0.001
Body mass index (kg/m2) 28 ± 4.8 28 ± 5.9 0.61
History of CAD 68 (39%) 55 (28%) 0.03
Diabetes 62 (36%) 51 (26%) 0.05
Hypertension 122 (70%) 138 (71%) 0.83
Current smoking 22 (13%) 18 (9.3%) 0.30
LDL cholesterol (mg/dL) 113 ± 64 116 ± 87 0.72
Family history of CAD 48 (28%) 42 (22%) 0.19
Chronic renal disease 9 (5.3%) 7 (3.6%) 0.45
Plasma creatinine (mg/dL) 0.95 (0.80 - 1.20) 0.80 (0.70 - 1.15) 0.10
Current statin therapy 85 (49%) 91 (47%) 0.71
Current aspirin therapy 75 (43%) 76 (39%) 0.44
Chest Pain Characteristics
Left side location 137 (79%) 156 (81%) 0.70
Oppressive nature 97 (57%) 95 (49%) 0.14
Irradiation to neck 39 (23%) 51 (26%) 0.42
Irradiation to left arm 57 (33%) 53 (27%) 0.24
Vagal symptoms 61 (36%) 78 (40%) 0.35
Number of episodes 1 (1 - 2) 1 (1 - 3) 0.81
Duration (minutes) 40 (15 - 120) 40 (10 - 150) 0.82
Intensity (1 - 10 scale) 7.4 ± 2.5 7.1 ± 2.6 0.31
Relief with nitrate 84 (50%) 72 (37%) 0.02
Similar to previous infarction 70 (42%) 63 (33%) 0.08
Worsening with compression 7 (4.1%) 26 (13%) 0.002
Worsening with position 24 (14%) 36 (19%) 0.23
Worsening with arm movement 7 (4.0%) 16 (8.2%) 0.097
Worsening with deep breath 13 (7.5%) 36 (19%) 0.002
Laboratory Tests at Admission
Ischemic changes on ECG 120 (68%) 73 (38%) < 0.001
Positive troponin 116 (66%) 60 (31%) < 0.001
X-ray and clinical signs of LVF 26 (15%) 5 (2.6%) < 0.001
NT-proBNP (pg/mL) 363 (105 - 1850) 57 (20 - 235) < 0.001
Plasma glucose (mg/dL) 120 (97 - 189) 112 (92 - 145) 0.22
C-reactive protein (mg/L) 7.3 (2.3 - 15) 5.7 (1.4 - 15) 0.09
White cell count 8.790 ± 4.300 7.701 ± 2.865 0.004
Hemoglobin (g/dL) 14.1 ± 1.9 13.7 ± 1.7 0.06

CAD: coronary artery disease; LVF: left ventricular failure. A family history of CAD implies in the presentation of the disease in a first-degree relative before the age of 55 years (females) or 45 years (males).