Table III.
Genotype and allele variant frequencies in patients and controls
| ITGB3(rs5918) | Patients (n = 132) | Controls (n = 122) | OR (95% CI) | P-value |
|---|---|---|---|---|
| Codominant model: | ||||
| TT | 88 (66.67%) | 101 (85.2%) | 1 | |
| TC | 30 (22.7%) | 18 (14.8%) | 0.523 (0.273–1.002) | 0.051 |
| CC | 14 (10.6%) | 3 (0.0%) | 0.187 (0.052–0.671) | 0.010 |
| Dominant model: | ||||
| TT | 88 (66.7%) | 101 (82.8%) | ||
| TC + CC | 44 (33.3%) | 21 (17.2%) | 2.40 (1.33–4.35) | 0.003 |
| Recessive model: | ||||
| CC | 14 (10.6%) | 3 (2.5%) | ||
| TC + TT | 118 (89.4%) | 119 (97.5%) | 4.71 (1.32–1.608) | 0.0067 |
| Allele frequency: | ||||
| T | 206 (78.0%) | 220 (90.2%) | ||
| C | 58 (22.00%) | 24 (9.8%) | 0.387 (0.232–0.644) | < 0.001 |
OR – odds ratio, CI – confidence interval.