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Structural format categories for BsAbs
| IgG‐like formats | Non‐IgG‐like formats |
|---|---|
| Quadroma | scFv based BsAbs |
| Knob‐into‐holes | Nanobodies |
| Dual variable domains Ig | Dock and lock methods |
| IgG‐single‐chain Fv (scFv) | Dual affinity retargeting molecules (DARTs) |
| Two‐in‐one Fab (or Dual action Fab) | |
| Half molecule exchange | |
| Κλ‐bodies |
