Table 1. CFTR expression in ALL and CML samples relative to the HBE cell line.
All ALL | T-ALL | B-ALL Ph- | B-ALL Ph+ | CML-CP | CML-BC | Normal | |
---|---|---|---|---|---|---|---|
Mean | 1.386 | 2.712 | 0.432 | 1.613 | 0.060 | 1.360 | 0.068 |
SD | 0.303 | 0.970 | 0.157 | 0.502 | 0.012 | 0.561 | 0.005 |
Median | 0.395 | 1.226 | 0.040 | 0.820 | 0.060 | 0.960 | 0.060 |
Min | 0.050 | 0.050 | 0.040 | 0.050 | 0.020 | 0.15 | 0.010 |
Max | 8.460 | 8.460 | 2.080 | 7.950 | 0.100 | 3.630 | 0.160 |
>>normal | 24 | 7 | 7 | 10 | 0 | 4 | 0 |
≤normal | 26 | 3 | 13 | 10 | 6 | 2 | 50 |
Total number | 50 | 10 | 20 | 20 | 6 | 6 | 50 |
NOTE: T-ALL: T-cell ALL samples; B-ALL: B-cell ALL samples; Ph+: all samples containing the Philadelphia chromosome; Ph−: samples not containing the Philadelphia chromosome; SD: standard deviation.
>> normal: sample values with high expression of CFTR based on the range of expression observed in normal human MNCs;
≤ normal: sample values with low expression of CFTR based on the range of expression observed in normal human MNCs.