Table 2. Univariate and multivariate analyses of overall survival in the SEER cohort.
| Variables | univariate analysis | multivariate analysis | |
|---|---|---|---|
| P Value | HR (95% CI) | P Value | |
| Age, years | <0.001 | ||
| 15-44 | 0.126(0.096-0.165) | <0.001 | |
| 45-54 | 0.187(0.149-0.235) | <0.001 | |
| 55-64 | 0.236(0.195-0.285) | <0.001 | |
| 65-74 | 0.339(0.284-0.405) | <0.001 | |
| 75-84 | 0.543(0.458-0.643) | <0.001 | |
| 85+ | Reference | ||
| Race | <0.001 | 0.173 | |
| White | |||
| Black | |||
| Other* | |||
| Sex | <0.001 | ||
| Female | 0.731(0.646-0.828) | <0.001 | |
| Male | Reference | ||
| Marital status | <0.001 | 0.205 | |
| Unmarried | |||
| Married | |||
| Grade | <0.001 | ||
| I | 0.308(0.229-0.415) | <0.001 | |
| II | 0.700(0.589-0.832) | <0.001 | |
| III | 0.958(0.829-1.107) | 0.557 | |
| IV | Reference | ||
| Laterality | 0.697 | ||
| Left | |||
| Right | |||
| Site | <0.001 | ||
| Parotid | 0.752(0.643-0.879) | <0.001 | |
| Submandibular | Reference | ||
| Sublingual | 0.584(0.286-1.193) | 0.140 | |
| T stage | <0.001 | ||
| T1 | 0.269(0.206-0.352) | <0.001 | |
| T2 | 0.430(0.337-0.548) | <0.001 | |
| T3 | 0.615(0.487-0.776) | <0.001 | |
| T4a | 0.711(0.565-0.894) | 0.004 | |
| T4b | Reference | ||
| N stage | <0.001 | ||
| N0 | 0.409(0.265-0.608) | <0.001 | |
| N1 | 0.629(0.406-0.946) | 0.026 | |
| N2a | 0.927(0.509-1.623) | 0.747 | |
| N2b | 0.770(0.490-1.134) | 0.170 | |
| N2c | 0.477(0.256-0.890) | 0.020 | |
| N3 | Reference | ||
| M stage | <0.001 | ||
| M0 | 0.341(0.281-0.414) | <0.001 | |
| M1 | Reference | ||
| Surgery Performed | <0.001 | ||
| Yes | 0.415(0.350-0.493) | <0.001 | |
| None | Reference | ||
| Radiation | <0.001 | ||
| Yes | 0.778(0.687-0.880) | <0.001 | |
| None | Reference | ||
*Other including American Indian/AK Native, Asian/Pacific Islander.
Abbreviations: CI; confidence interval; HR, hazard ratio.