Table 2. NSCLC associated microRNAs.
microRNA | Chromosome | Permutation p-value | Corrected p-value | No. of Studies | Seed family | microRNA Cluster |
---|---|---|---|---|---|---|
Upregulated | ||||||
miR-21-5p | 17q23.1 | 4.68E-29 | 9.38E-26 | 24 | miR-21-5p/590-5p | - |
miR-210 | 11p15.5 | 3.82E-26 | 7.66E-23 | 20 | miR-210 | - |
miR-205-5p | 1q32.2 | 1.12E-21 | 2.24E-18 | 15 | miR-205-5p | - |
miR-182-5p | 7q32.2 | 9.38E-18 | 1.88E-14 | 16 | miR-31-5p | - |
miR-31-5p | 9p21.3 | 6.72E-16 | 1.35E-12 | 14 | miR-182-5p | miR-182/96/183 |
miR-183-5p | 7q32.2 | 1.04E-13 | 2.09E-10 | 14 | miR-183-5p | miR-182/96/183 |
miR-96-5p | 7q32.2 | 1.28E-12 | 2.57E-09 | 12 | miR-96-5p/1271-5p | miR-182/96/183 |
Downregulated | ||||||
miR-126-3p | 9q34.3 | 4.30E-25 | 8.62E-22 | 21 | miR-126-3p | - |
miR-143-3p | 6q13 | 8.24E-21 | 1.65E-17 | 19 | miR-30abcdef-5p/384-5p | miR-30a/c-2 |
miR-451a | 17q11.2 | 1.95E-20 | 3.91E-17 | 18 | miR-451a | miR-4732/144/451 |
miR-486-5p | 8p11.21 | 5.15E-19 | 1.03E-15 | 17 | miR-486-5p | - |
miR-145-5p | 5q32 | 2.21E-12 | 4.44E-09 | 15 | miR-145-5p/5195-3p | miR-143/145 |
miR-143-3p | 5q32 | 3.02E-12 | 6.05E-09 | 14 | miR-143-3p/4770/6088 | miR-143/145 |
miR-30d-5p | 8q24.22 | 8.41E-13 | 1.69E-09 | 13 | miR-30abcdef/384-5p | miR-30b/d |
miR-139-5p | 11q13.4 | 1.21E-10 | 2.43E-07 | 11 | miR-139-5p | - |
miR-126-5p | 9q34.3 | 3.60E-09 | 7.22E-06 | 11 | miR-126-5p | - |
miR-338-3p | 17q25.3 | 1.18E-11 | 2.37E-08 | 11 | miR-338-5p | miR-338/657/1250/3065 |