Table 3. Frequency of autoantibodies against GRP78 in human serum samples by ELISA.
Type of serum | No. tested | Frequency(patients with autoantibody/total patients with disease) |
---|---|---|
HCC | 173 | 7.5% (13/173)** |
LC | 110 | 10.0% (11/110)** |
CH | 110 | 6.4% (7/110) |
NHS | 101 | 0% (0/101) |
Cutoff value, mean + 2SD of NHS samples; **P <0.01, P value relative to NHS
Abbreviations: GRP78, 78 kDa glucose regulated protein; HCC, hepatocellular carcinoma; LC, liver cirrhosis; CH, chronic hepatitis; NHS, normal human serum.