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. 2017 Feb 15;8(15):24949–24963. doi: 10.18632/oncotarget.15327

Figure 4. Overexpression of miR-29a inhibits GSC oncogenesis by downregulating QKI-6.

Figure 4

A. Overexpression of miR-29a inhibited GSC proliferation by downregulating QKI-6. B. Overexpression of miR-29a combined with QKI-6 inhibition led to the highest apoptosis rate in GSCs. C. Overexpression of QKI-6 reversed the inhibitory effects of miR-29a overexpression on GSC migration and invasion. Representative images and accompanying statistical plots are presented. Values represent the mean ± SD from five independent experiments.*P<0.05 vs. agomir-29a-NC group,#P<0.05 vs. agomir-29a-NC+pGPU6-shQKI-6-NC group, &P<0.05 vs. agomir-29a group. Scale bar represents 80 μm. The photographs were taken at 200× magnification.