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. 2017 Feb 15;8(15):24949–24963. doi: 10.18632/oncotarget.15327

Figure 5. WTAP is a direct target of QKI-6.

Figure 5

A. IHC assay images of WTAP expression in glioma tissues and normal brain tissues on tissue microarray sections. The photographs were taken at 40× magnification. B. WTAP expression was greater in GSCs (CD133+) than in non-GSCs (CD133-) in Western blot analysis with GAPDH as an endogenous control. *P<0.01 vs. non-GSC group. C. WTAP expression was significantly lower in miR-29a-overexpressing GSCs-U87, GSCs-U251 and GSCs-GTD than in their respective NC groups. *P<0.05 vs. agomir-29a-NC group. D. The protein expression of WTAP in GSCs after QKI-6 overexpression and inhibition. *P<0.05 vs. pGPU6-shQKI-6-NC group,#P<0.05 vs. pIRES2-QKI-6-NC group. For B-D, values represent the mean ± SD from five independent experiments. IDVs represent the relative integrated density values.