Figure 6. Decreased expression of CD1d in multiple KO mice.
A. qPCR analysis of CD3ε, CD4, CD8b1, Vα14-Jα281 and CD1d expression was performed on lung tissues from B16F10 melanoma-carrying WT or multiple KO mice (n = 6-8). Expression of genes was evaluated relative to GAPDH and normalized to naïve mice. Results are presented as mean ± SEM. Statistical calculations were performed using the Mann Whitney test. B. Correlation between the expression of CD1d with expression of melanoma-specific genes: DCT and GP100; Nonparametric Spearman correlation.