Table 2. Univariable and multivariable (Cox) analyses of prognostic factors for overall survival in the mutation analysis group.
| No. deaths /No. patients | Univariable | Multivariable | ||
|---|---|---|---|---|
| p-value | HR [95% CI] | p-value | ||
| Mutation group | 0.22 | 0.26 | ||
| All wildtype | 34/50 | Ref | ||
| EGFR/ALK+ | 6/11 | 0.8 [0.3 ; 2.0] | ||
| Other mutation | 13/17 | 1.6 [0.8 ; 3.2] | ||
| Performance status | 0.08 | 0.08 | ||
| 0 | 23/38 | Ref | ||
| ≥ 1 | 30/40 | 1.7 [0.9 ; 2.9] | ||
| Stage | 0.17 | 0.10 | ||
| IIIA | 29/47 | Ref | ||
| IIIB | 24/31 | 1.7 [0.9 ; 3.0] | ||
| Radiotherapy dose | 0.55 | |||
| < 66 Gy | 20/27 | |||
| ≥ 66 Gy | 33/51 | |||
| Thoracic surgery | 0.16 | 0.20 | ||
| No | 42/60 | Ref | ||
| Yes | 11/18 | 0.6 [0.3 ; 1.3] | ||
| PET scan | 0.05 | 0.002 | ||
| No | 11/12 | Ref | ||
| Yes | 42/66 | 0.3 [0.1 ; 0.6] | ||
HR = Hazard ratio; CI = Confidence interval; Ref = reference group.
Variables are included in the multivariable Cox model only if univariable p-value < 0.20, except for mutation group since it is the studied variable.