Table 2. Pooled analysis of association of metformin use and survival of PC concurrent with DM.
N | Sample size | HR | Ph | I2 | |
---|---|---|---|---|---|
Total | 10 | 9318 | 0.84 | 0.006 | 60.8% |
(0.73-0.96) | |||||
Country | |||||
Asian | 3 | 544 | 0.65(0.52-0.80) | 0.83 | 0.0% |
Western | 7 | 8774 | 0.90(0.78-1.03) | 0.028 | 57.6% |
Quality | |||||
High | 7 | 8495 | 0.81(0.70-0.95) | 0.012 | 63.3% |
Low | 3 | 823 | 0.88(0.60-1.29) | 0.67 | 63.1% |
Exposure | |||||
Before PC diagnose | 3 | 4740 | 1.00(0.81-1.24) | 0.1 | 56.6% |
After PC diagnose | 3 | 2359 | 0.76(0.52-1.11) | 0.028 | 72.0% |
Publication bias test | |||||
Begg's test | p=1.00 | ||||
Egger's test | p=0.896 |
Ph: P for heterogeneity.