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. 2017 Feb 25;8(15):25242–25250. doi: 10.18632/oncotarget.15692

Table 2. Pooled analysis of association of metformin use and survival of PC concurrent with DM.

N Sample size HR Ph I2
Total 10 9318 0.84 0.006 60.8%
(0.73-0.96)
Country
 Asian 3 544 0.65(0.52-0.80) 0.83 0.0%
 Western 7 8774 0.90(0.78-1.03) 0.028 57.6%
Quality
 High 7 8495 0.81(0.70-0.95) 0.012 63.3%
 Low 3 823 0.88(0.60-1.29) 0.67 63.1%
Exposure
 Before PC diagnose 3 4740 1.00(0.81-1.24) 0.1 56.6%
 After PC diagnose 3 2359 0.76(0.52-1.11) 0.028 72.0%
Publication bias test
 Begg's test p=1.00
 Egger's test p=0.896

Ph: P for heterogeneity.