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. 2017 Mar 7;8(15):25433–25441. doi: 10.18632/oncotarget.15989

Table 4. Sensitivity, specificity, positive (PPV) and negative predictive values of HER-2 overexpression in predicting DFS and PFS.

HER-2 overexpression Disease-Free Survival Progression-Free Survival
Sensitivity 58% (95% CI 43%-73%) 65% (95% CI 42%-87%)
Specificity 83% (95% CI 68%-98%) 65% (95% CI 51%-79%)
PPV 86% (95% CI 74%-99%) 41% (95% CI 22%-59%)
NPV 53% (95% CI 37%-69%) 83% (95% CI 71%-96%)