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. 2017 Mar 9;8(15):25455–25468. doi: 10.18632/oncotarget.16037

Table 7. Correlation between treatment groups and clinical characteristics, FISH abnormalities and IGHV mutation status.

Chlorambucil FCR p value
Median age (years) (range) 68 (44-91) 56 (26-76) p<0.01
Binet stage N (%)
A 27 (53%) 5 (12.8%)
B 14 (27.4%) 18 (46.2%) p<0.01
C 10 (19.6%) 16 (41%)
Total 51 39
IGHV mutational status N (%)
Unmutated 7 (21%) 18 (72%)
Mutated 26 (79%) 7 (28%) p<0.01
Total 33 25
FISH abnormalities N (%)
Del13q14/normal/trisomy12 34 (79%) 24 (63%)
Del11q23/Del17p 9 (21%) 14 (37%) p=0.1
Total 43 38