Table 7. Correlation between treatment groups and clinical characteristics, FISH abnormalities and IGHV mutation status.
Chlorambucil | FCR | p value | |
---|---|---|---|
Median age (years) (range) | 68 (44-91) | 56 (26-76) | p<0.01 |
Binet stage | N (%) | ||
A | 27 (53%) | 5 (12.8%) | |
B | 14 (27.4%) | 18 (46.2%) | p<0.01 |
C | 10 (19.6%) | 16 (41%) | |
Total | 51 | 39 | |
IGHV mutational status | N (%) | ||
Unmutated | 7 (21%) | 18 (72%) | |
Mutated | 26 (79%) | 7 (28%) | p<0.01 |
Total | 33 | 25 | |
FISH abnormalities | N (%) | ||
Del13q14/normal/trisomy12 | 34 (79%) | 24 (63%) | |
Del11q23/Del17p | 9 (21%) | 14 (37%) | p=0.1 |
Total | 43 | 38 |