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. 2017 Mar 10;8(15):25582–25598. doi: 10.18632/oncotarget.16106

Table 3. Clinical features of the patients enrolled in this study.

Patient Sex (M/F) Age (years old) Side of tumor Date of surgery (year, month) Histological diagnosis (WHO classification) Months of survival Preoperative KPS Postoperative KPS Preoperative Deficit Postoperative Deficit (at the discarge) Postoperative treatment Recurrence
1 M 77 Right fronto-pariel 2011, Sept. IV grade 6 70 70 Moderate left hemiparesis No further deficit than preop time CT + RT (Stupp protocol*), Levetiracetam After 6 months
2 M 75 Right fronto-temporal 2013, Sept. IV grade 11 80 80 Mild ideo-motor apraxia, mild left lower limb deficit with some difficulties with walking No further deficit than preop time CT + RT (Stupp protocol*), Levetiracetam After 10 months
3 F 72 Right fronto-temporal 2013, Sept. IV grade 11 80 90 Mild ideo-motor slowing, mild motor deficit in left upper limb Improvement of ideo-motor slowing and preop motor deficit CT + RT (Stupp protocol*), Levetiracetam No
4 M 36 Left Temporal 2013, Sept. III grade Living 100 100 No deficit No deficit RT No
5 F 45 Left frontal 2013, Oct. II grade Living 90 90 Dysphasia Improvement of preoperative dysphasia RT after the first operation. CT after the second operation. Levetiracetam After 22 month (Re-operation)
6 F 48 Left frontal 2013, Dec. II grade Living 90 100 Dysphasia Improvement of preoperative dysphasia RT. Levetiracetam No
7 F 65 Left fronto-temporal 2013, Nov. IV grade 17 80 80 Right hemiparesis (Moderate in upper limb, mild in lower limb) No further deficit than preop time CT+ RT (Stupp protocol*). Levetiracetam After 13 months
8 F 37 Right temporal 2014, Nov. IV grade Living 90 90 No deficit No deficit CT+ RT (Stupp protocol*). Levetiracetam No
9 F 68 Left Temporo-parietal 2015, Oct. IV grade 14 90 90 Mild ideo-motor slowing, very mild right upper limb deficit No further deficit than preop time RT + CT (Stupp protocol*). Levetiracetam After 10 months
10 F 27 Left temporal 2016, Feb. II grade Living 100 100 Dysphasia No deficit RT + CT (Stupp protocol*). Levetiracetam No

*Stupp protocol: Adjuvant treatment with radiotherapy (RT) and chemotherapy (CT). Focal radiotherapy was delivered once daily at 2Gy per fraction, 5 day/week, for a total of 60 Gy, as prescribed by the radiation oncologist, according to the guidelines of the International Commission on Radiological Units. Concomitant treatment with temozolomide was prescribed by the oncologist at a dose of 75 mg/m2 for each day of radiation treatment. Four weeks after radiotherapy, patients received adjuvant temozolomide chemotherapy, 150 to 200 mg/m2 on days 1 to 5 at 28-day intervals. All patients were subjected to radical exeresis, except patient #10 subjected to a subtotal exeresis.