Table 1.
Patients’ characteristics and summary of the radiotherapy.
| Characteristics | Number of patients | |
|---|---|---|
| Number of patients | 50 | |
| Age (years) | 73.5 (48–89) | |
| Tumor background | ||
| Hepatocellular carcinoma | 36 | |
| Metastatic liver tumor | 13 | |
| Cholangiocellular carcinoma | 1 | |
| Background liver | ||
| Normal liver (metastatic liver tumor) | 13 | |
| Child–Pugh classification | A | 29 |
| B | 8 | |
| Summary of radiotherapy | |
|---|---|
| Total prescription dose (Gy) | 50.0 (40.0–65) |
| Number of fractions | 9 (4–25) |
| Fraction size (Gy) | 5.7 (2.6–11) |
| BED10 (Gy) | 80.0 (56.0–115.5) |
| PTV (cm3) | 80.2 (17.1–1242.7) |
| Volume of the whole liver (cm3) | 1048.5 (683–1701) |
| Volume of the background liver (cm3) | 929.4 (574.2–1574.7) |
| Mean physical dose for the whole liver (Gy) | 14.8 (5.34–35.93) |
| Mean physical dose for the background liver (Gy) | 11.1 (3.91–24.96) |
| Mean BED2 for the whole liver (Gy) | 36.8 (9.26–99.91) |
| Mean BED2 for the background liver (Gy) | 22.5 (7.49–58.88) |
HCC = hepatocellular carcinoma; PTV = planning target volume; BED = biologically effective dose.
The background liver was defined as the whole liver minus the PTV.