Table 4. Relative risk of cardiovascular events with non-selective NSAIDs compared to controls in a meta-analysis (McGettigan and Henry).
Non-selective NSAIDs | ||||||
Naproxen | Diclofenac | Ibuprofen | Indomethacine | Piroxicam | Non-selective NSAIDs combined | |
Case-control studies | 0.96(0.84-1.10) | 1.36(1.21-1.54) | 1.06(0.95-1.18) | 1.30(1.07-1.60) | 1.06(0.70-1.59) | 1.10(0.98-1.24) |
Cohort studies | 0.94(0.85-1.04) | 1.36(0.51-3.65) | 1.12(0.90-1.38) | -- | -- | 1.10(0.95-1.29) |
Case-control and cohort studies combined | 0.97(0.87-1.07) | 1.40(1.16-1.70) | 1.07(0.97-1.18) | 1.30(1.07-1.60) | 1.06(0.70-1.59) | 1.10(1.00-1.21) |