Figure 8.
Mean distance traveled (±SEM) on the test day. On the pretreatment day (PD 19), rats were injected with saline or 30 mg/kg cocaine, with behavioral assessment lasting 30 min (data not shown). On the preinjection day (PD 20), rats were injected with EEDQ (0, 7.5, or 15 mg/kg). On the test day (PD 21), all rats were challenged with 20 mg/kg cocaine. The testing session lasted 120 min.
* Significantly different from the 0 mg/kg EEDQ–Saline group (open bars)
† Significantly different from the 0 mg/kg EEDQ–Cocaine group (black bars).