4.

Multivariate analysis of prognostic factors for survival and tumor recurrence (N=120)

Variables	Survival			Recurrence
	HR (95% CI)	P		HR (95% CI)	P
95% CI, 95% confidence interval; HR, hazard ratio.
Age (years)
<55	1			1
≥55	1.339 (0.853–2.102)	0.205		0.926 (0.585–1.467)	0.743
T status
T1+T2	1			1
T3	1.577 (0.769–3.234)	0.214		1.101 (0.543–2.230)	0.790
N category
N1	1			1
N2+N3	1.866 (1.177–2.960)	0.008		1.482 (0.922–2.384)	0.105
Differentiation
Well	1			1
Moderate	1.252 (0.671–2.336)	0.479		1.045 (0.566–1.929)	0.889
Poor	1.287 (0.673–2.464)	0.446		1.075 (0.555–2.083)	0.831
Adjuvant chemotherapy
No	1			1
Yes	0.479 (0.285–0.803)	0.005		0.448 (0.260–0.773)	0.004