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. 2017 May 9;4:15. doi: 10.3389/fnut.2017.00015

Figure 10.

Figure 10

The sugar binging-like behavior (SBLB)-inducing protocol fulfils all requirements to be considered a valid SBLB-inducing protocol. Upper left panel: Volume of food consumed during test periods compared to the animal’s theoric gastric capacity during the full duration of the SBLB-inducing protocol (12 tests), during the administration of fluoxetine (3 tests) and during the washout period (3 tests). Two-way ANOVA with Sidak’s multiple comparison test (***P < 0.001), one-way ANOVA for repeated measures with Dunnett multiple comparison test (++P < 0.01, +++P < 0.001). Lower left panel: Mean% of the theoric gastric capacity used during the last three tests of the SBLB protocol, during the administration of fluoxetine (10 mg/kg IP), and during the washout period. Two-way ANOVA with Sidak’s multiple comparison test (***P < 0.001, **P < 0.02, *P < 0.5). Upper right panel: Milliliters of sucrose solution consumed during test periods before, during, and after the administration of fluoxetine 10 mg/kg. One-way ANOVA with Dunnett multiple comparison test (*P < 0.01, **P < 0.001, ***P < 0.001). Lower right panel: Mean sucrose solution consumption during the last three test periods of the SBLB protocol, during the administration of fluoxetine and during the washout period. One-way ANOVA with Sidak’s multiple comparison test (*P < 0.05).