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. 2017 May 4;10:2413–2424. doi: 10.2147/OTT.S130087

Table 2.

CTCs and disease-related characteristics

Characteristics Number TCTCs ECTCs EMCTCs MCTCs
Pathologic type
 Adenocarcinoma 26 5.5 (1.75, 12.25) 0.5 (0, 2) 4 (0, 8.25) 0 (0, 1.25)
 Adenosquamous 3 8 (2, 10) 1 (0, 1) 6 (1, 8) 0 (0, 3)
Location
 Right lung 19 7 (1, 8) 0 (0, 1) 2 (0, 8) 0 (0, 1)
 Left lung 12 5.5 (3.25, 13) 1 (0, 3.5) 4.5 (0.75, 9.75) 0 (0, 2.75)
Tumor stage
 III 5 1 (0, 7) 0 (0, 0)* 1 (0, 7) 0 (0, 0)
 IV 24 7 (3, 12.75) 1 (0, 2)* 4 (1, 8.75) 0 (0, 2)
T
 1 2 4 (1, 7) 3 (1, 5) 1 (0, 2) 0 (0, 0)
 2 2 6.5 (3, 10) 0.5 (0, 1) 4 (2, 6) 2 (1, 3)
 3 5 2 (0, 27) 0 (0, 16) 1 (0, 10) 0 (0, 1.5)
 4 20 7.5 (3.25, 12.75) 0.5 (0, 2) 4.5 (1, 8.75) 0 (0, 1.75)
M
 M0 5 1 (0, 7) 0 (0, 0)* 1 (0, 7) 0 (0, 0)
 M1a 2 6.5 (0, 13) 0 (0, 0)* 5.5 (0, 11) 1 (0, 2)
 M1b / / / / /
 M1c 22 7 (3, 12.5) 1 (0, 2.5)* 4 (1, 8.25) 0 (0, 2.25)
N
 N0 2 3.5 (0, 7) 1 (0, 2)* 2 (0, 4) 0.5 (0, 1)
 N1 0 / / / /
 N2 10 3.5 (0, 8.5) 0 (0, 0.25)* 3 (0, 6.5) 0 (0, 3.25)
 N3 17 7 (3.5, 13.5) 1 (0, 4.5)* 6 (1, 11) 0 (1, 1.5)

Notes:

*

P<0.05; statistical description: median (figures outside the parentheses) and interquartile range (figures in the parentheses).

Abbreviations: CTCs, circulating tumor cells; ECTCs, epithelial circulating tumor cells; EMCTCs, epithelial–mesenchymal circulating tumor cells; MCTCs, mesenchymal circulating tumor cells; TCTCs, total CTCs.