Figure 1.
Cumulative incidence of DM with patients classified into 4 DMARD groups (A) and 5 DMARD groups (B). (A) The cumulative incidence of DM in the CSA group was significantly higher than that in the other 3 groups (vs anti-TNF: P=0.014; vs HCQ: P=0.022; vs other nonbiologic DMARDs: P=0.013). (B) The cumulative incidence of DM was similar in the CSA group and the group that used anti-TNF without HCQ, and significantly lower in the other 3 groups (anti-TNF + HCQ, HCQ, other DMARDs); the cumulative incidence of DM in the anti-TNF + HCQ group was significantly lower than in the other 4 groups (vs anti-TNF without HCQ: P<0.001; vs CSA: P<0.001; vs HCQ: P=0.015; vs other DMARDs: P=0.031).
Abbreviations: DM, diabetes mellitus; DMARD, disease-modifying antirheumatic drug; CSA, cyclosporine; TNF, tumor necrosis factor; HCQ, hydroxychloroquine.