Table 2. Static dual-energy CT perfusion imaging studies.

Author	N.	CT technology	Analysis	Reference standard	SE (%)	SP (%)	PPV (%)	NPV (%)	Dose (mSv)
Ko et al., 2012 (35)	45	First DSCT	Iodine Map (for vessel)	QCA	89	74	80	85	5.7
Delgado et al., 2013 (36)	56	Second DSCT	Iodine Map (for segment)	MRI 1.5T	76	99	89	98	5.2
Meinel et al., 2014 (37)	55	Second DSCT	Iodine Map (for segment)	SPECT	99	97	92	100	7.1
Kido et al., 2014 (53)	21	First/Second DSCT	Iodine Map (for vessel)§	QCA	67	92	84	82	7.7
Ko et al., 2014 (54)	40	First DSCT	Iodine Map (for vessel)	QCA + MRI 3T§	87	79	71	91	4.6
Ko et al., 2014 (55)	100	First DSCT	Iodine Map (for vessel)	QCA + MRI 1.5T and 3T§	88	79	73	91	4.2
Kim et al., 2014 (56)	50	Second DSCT	Iodine Map (for segment)	MRI 1.5T	77	94	53	98	6.5

All the studies used adenosine at a dose of 0.14 mg/kg/min. Meinel et al. (37) used also a single injection of regadenoson at a dose of 0.4 mg. CT, computed tomography; DSCT, dual-source CT scanner; N., number of patients; mSv, millisievert; MRI, magnetic resonance imaging; NPV, negative predictive value; PPV, positive predictive value; QCA, quantitative coronary angiography; SE, sensitivity; SP, specificity; SPECT, myocardial perfusion scan. ^§, accuracy of CT perfusion integrated with the coronary anatomic data.