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. 2017 Apr;7(2):196–205. doi: 10.21037/cdt.2017.04.08

Table 1. Diagnostic accuracy of cardiac PET vs. SPECT for detecting CAD.

Variables Mc Ardle et al. [2012] Parker et al. [2012] Bateman et al. [2006]
Patients, n 3,099 11,862 224
Type of study Meta-analysis Meta-analysis Single-center study
Isotope
   PET Rb-82 Rb-82/13N Ammonia Rb-82
   SPECT Tc 99m-sestamibi Tc 99m-sestamibi Tc 99m-sestamibi
Sensitivity
   PET 90% 92% 86%
   SPECT 85% 88% 81%
Specificity
   PET 88% 81% 100%
   SPECT 85% 75% 66%

PET, positron emission tomography; SPECT, single photon emission computed tomography; CAD, coronary artery disease.