Table 1. Diagnostic accuracy of cardiac PET vs. SPECT for detecting CAD.
Variables | Mc Ardle et al. [2012] | Parker et al. [2012] | Bateman et al. [2006] |
---|---|---|---|
Patients, n | 3,099 | 11,862 | 224 |
Type of study | Meta-analysis | Meta-analysis | Single-center study |
Isotope | |||
PET | Rb-82 | Rb-82/13N Ammonia | Rb-82 |
SPECT | Tc 99m-sestamibi | Tc 99m-sestamibi | Tc 99m-sestamibi |
Sensitivity | |||
PET | 90% | 92% | 86% |
SPECT | 85% | 88% | 81% |
Specificity | |||
PET | 88% | 81% | 100% |
SPECT | 85% | 75% | 66% |
PET, positron emission tomography; SPECT, single photon emission computed tomography; CAD, coronary artery disease.