Table 2. Prognostic value of PET-CFR in women as compared to men.

Variables	Murthy et al. [2011]	Taqueti et al. [2016]
Patients, n	1,218 (67% women)	329 (43% women)
End point	MACE (n=75)	MACE (n=74)
Follow up, years	1.3	3
PET tracer	13N Ammonia/Rb-82	13N Ammonia/Rb-82
Preserved CFR	>2	>2
Major findings	Coronary microvascular dysfunction (as defined as CFR <2) was a powerful incremental predictor of MACE, both in men and women despite normal stress perfusion imaging by PET	As compared to men, women referred for invasive evaluation of CAD demonstrated less obstructive epicardial CAD, but greater adjusted risk of cardiovascular events. Only women with severely impaired coronary flow reserve (<1.6) demonstrated increased risk relative to men

PET, positron emission tomography; CFR, coronary flow reserve; MACE, major adverse cardiac events; CAD, coronary artery disease.