Table 4.
Comparison of blood and sputum counts between baseline and exacerbation for PPM positive and PPM negative groups
| BLOOD | PPM positive n = 78 | PPM negative n = 31 | ||||
| Baseline | Exacerbation | p value | Baseline | Exacerbation | p value | |
| White blood cell count (x109/L) | 7.4 [4.4–15.6] | 8.9 [2.8–20.5] | <0.0001 | 7.00 [5.03–13.4] | 8.90 [4.90–15.40] | <0.0001 |
| Neutrophil count (x109/L) | 4.95 [2.95–12.23] | 6.13 [1.42–18.12] | <0.0001 | 4.38 [2.97–8.29] | 5.50 [2.36–10.98] | 0.004 |
| Eosinophil blood count (x109/L) | 0.23 [0.05–0.90] | 0.17 [0.00–0.76] | 0.008 | 0.22 [0.04–0.57] | 0.23 [0.02–0.78] | 0.08 |
| Lymphocyte blood count (x109/L) | 1.70 [0.75–3.67] | 1.89 [0.44–4.66] | 0.13 | 1.67 [1.00–4.25] | 1.79 [0.50–3.03] | 0.69 |
| Monocyte blood count (x109/L) | 0.55 [0.28–1.41] | 0.68 [0.26–1.87] | <0.0001 | 0.6 [0.4–1.06] | 0.77 [0.42–1.43] | <0.0001 |
| SPUTUM | PPM positive n = 22 | PPM negative n = 8 | ||||
| Baseline | Exacerbation | p value | Baseline | Exacerbation | p value | |
| Total Cell count (x106/g) | 5.84 [0.63–84.56] | 10.58 [0.41–154.5] | 0.14 | 3.01 [0.25–5.27] | 6.51 [0.60–36.67] | 0.008 |
| Sputum Neutrophil count (x106/g) | 5.14 [0.02–82.44] | 9.79 [0.08–151.6] | 0.11 | 0.73 [0.16–3.61] | 5.19 [0.19–35.75] | 0.05 |
| Sputum Macrophage count (x106/g) | 0.74 [0.14–4.22] | 0.11 [0.00–1.55] | <0.0001 | 0.74 [0.04–2.16] | 0.07 [0.01–0.37] | 0.02 |
| Sputum Eosinophil count (x106/g) | 0.07 [0.00–0.52] | 0.01 [0.00–0.31] | 0.09 | 0.02 [0.01–0.50] | 0.03 [0.00–3.17] | 0.61 |
| Sputum Lymphocyte count (x106/g) | 0.00 [0.00–0.25] | 0.00 [0.00–0.27] | 0.11 | 0.00 [0.00–0.01] | 0.005 [0.00–0.09] | 0.31 |
| Sputum Epithelial count (x106/g) | 0.19 [0.00–2.32] | 0.16 [0.00–0.84] | 0.56 | 0.20 [0.04–0.30] | 0.24 [0.03–0.95] | 0.74 |
| Sputum Neutrophil % | 84.00 [3.00–97.75] | 90.75 [19.00–99.25] | 0.21 | 55.38 [7.00–83.53] | 78.00 [5.25–97.5] | 0.11 |
| Sputum Macrophage % | 11.12 [1.50–88.50] | 6.00 [0.50–70.25] | 0.28 | 26.88 [8.82–85.5] | 9.00 [1.5–35.5] | 0.02 |
| Sputum Eosinophil % | 0.75 [0.00–6.98] | 0.23 [0.00–2.00] | 0.046 | 1.88 [0.29–12.75] | 1.00 [0.00–86.5] | 0.38 |
| Sputum Lymphocyte % | 0.00 [0.00–0.25] | 0.00 [0.00–1.00] | 0.35 | 0.00 [0.00–2.50] | 0.13 [0.00–0.25] | 0.63 |
| Sputum Epithelial cell % | 2.13 [0.00–40.00] | 2.13 [0.00–54.76] | 0.89 | 7.68 [1.50–17.50] | 5.00 [0.75–11.00] | 0.25 |