Table 4.
List of a priori Clinically Defined Predictors and their Measurement
| Measurement | Value | Variable | Table |
|---|---|---|---|
| Laboratory | |||
| Number ESR tests | 85651, 85652 | CPT | CDW.OutpatProcedure |
| Number CRP tests | 86140 | CPT | CDW.OutpatProcedure |
| aCCP – (Y/N) | 86200 | CPT | CDW.OutpatProcedure |
| RF – (Y/N) | 86431 | CPT | CDW.OutpatProcedure |
| Number. complete blood counts | 85025 | CPT | CDW.OutpatProcedure |
| Number. chemistry panels ordered or any electrolyte | 80053, 82248, 82465, 82977, 83540, 83615, 84100, 84478, 84550 | CPT | CDW.OutpatProcedure |
| Radiology | |||
| Radiographs (Y/N) | 70010-79999 | CPT | CDW.OutpatProcedure |
| Number radiographs | Count of 70010-79999 | CPT | CDW.OutpatProcedure |
| Hand or foot (Y/N) (toes, fingers, wrist) | 73620, 73630, 73650, 73660, 73100, 73110,73120, 73130 | CPT | CDW.OutpatProcedure |
| C-spine (Y/N) | 72040, 75052 | CPT | CDW.OutpatProcedure |
| Other bone x-ray (Y/N) | Master file | CPT | CDW.OutpatProcedure |
| Clinic Visits | |||
| Any visit | Any | stopcode | CDW.outpatVisit |
| Rheumatology | 314 | stopcode | CDW.outpatVisit |
| Primary care | 323, 342 | stopcode | CDW.outpatVisit |
| Orthopedic | 60, 509 | stopcode | CDW.outpatVisit |
| Physical Rehabilitation | 201, 250 | stopcode | CDW.outpatVisit |
| Occupational Therapy | 21, 206, 460 | stopcode | CDW.outpatVisit |
| Number ED visits | 130, 101 | stopcode | CDW.outpatVisit |
| Utilization | |||
| Number Inpatient stay | Row count per person | Admission date | Inpatient.inpatient |
| Unique Drug class codes | Row count per person | VAdrugclasscode | CDW.Rxoutpat |
| Procedures | |||
| Any surgery | 10021-6990 | CPT | |
| Any surgery | Master file | ICD9 | CDW.outpatProcedure, inpatProcedure, inpatientCPT |
| Hand surgery | 26500, 26502, 26504, 26494, 26989 | CPT | CDW.Outpat.Procedure, inpatientCPT |
| Hand surgery | Master filea | ICD9 | CDW.inpatientProcedure |
| Any orthopedic (include spine) surgery | Master file | CPT | CDW.inpatientCPT, Outpat.Procedure |
| Joint injections | Master file | Jcode | CDW.Outpat.Procedure, inpatientCPT |
| Comorbidity | |||
| RDCI RA comorbidity score | See published paper | ICD9 | CDW.outpatDiagnosis |
| Rheumatoid lung involvement | 714.81 | ICD9 | CDW.outpatDiagnosis |
| Felty’s syndrome | 714.1 | ICD9 | CDW.outpatDiagnosis |
| Sjogrens | 710.2 | ICD9 | CDW.outpatDiagnosis |
| Assistive Devices | |||
| Cane (Y/N) | Master file | CPT/ICD9 procedure | CDW.outpatProcedure, inpatProcedure |
| Crutch (Y/N) | Master file | CPT/ICD9 procedure | CDW.outpatProcedure, inpatProcedure |
| Walker (Y/N) | Master file | CPT/ICD9 procedure | CDW.outpatProcedure, inpatProcedure |
| Wheelchair (Y/N) | Master file | CPT/ICD9 procedure | CDW.outpatProcedure, inpatProcedure |
| Other Assist Device (Y/N) | Master file | CPT/ICD9 procedure | CDW.outpatProcedure, inpatProcedure |
| Medications dispensed | |||
| Number NSAID | MS102 | VA drug Class | CDW.Rxoutpatfill |
| Number Non-biologic DMARD | String search - list below | drugnamewithoutdose | CDW.Rxoutpatfill |
| Methotrexate (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| Leflunomide (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| Sulfasalazine (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| Hydroxychloroquine (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| Azathioprine (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| TNFi (Y/N) | String search: etanercept, adalimumab, infliximab, golimumab, certolizumab | drugnamewithoutdose | CDW.MCA, Rxoutpatfill, outpatProcedure, TIU notes |
| Other biologics | rituximab, abatacept, anakinra, tocilizumab, | drugnamewithoutdose | CDW.MCA, Rxoutpatfill, outpatProcedure, TIU notes |
| Tofacitinib (Y/N) | String search | drugnamewithoutdose | CDW.Rxoutpatfill |
| Glucocorticosteroids (Y/N and Dose) | HS051 | VA drug Class | CDW.MCA and Rxoutpatfill |
| Minor DMARDs (Any Y/N) | Doxycyline, minocycline, auranofin, d-penicillamine, cyclosporine | drugnamewithoutdose | CDW.Rxoutpatfill |
| Smoking cessation medication (Y/N) | Chantix Nicotine substitutes | Drugnamewithoutdose | CDW.Rxoutpatfill |
| Processed Medication Data for DMARDs | |||
| Days since start med | All meds | drugnamewithoutdose | CDW.Rxoutpatfill |
| Days since end med (90-day gap to end) | All meds | drugnamewithoutdose | CDW.Rxoutpatfill |
| PDC from start therapy to end of observation period | All meds | drugnamewithoutdose | CDW.Rxoutpatfill |
| Demographics | |||
| Age | Age | DOB | CDW.patient |
| Gender | M/F | Gender | CDW.patient |
aMaster File = primary excel workbook containing all measured concepts and is available by request (brian.sauer@utah.edu)
ESR erythrocyte sedimentation rate, CRP c-reactive protein, PDC proportion of days covered