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. 2017 May 8;10:119. doi: 10.1186/s13068-017-0804-2

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Overall process cost and contributions by feed, separation stages, and tasks with varying biomass titer. a Overall process cost (Y1) and cost contribution (Y2) by feed, and active separation stages I and III. b Cost contribution (Y2) by the three tasks in stage I: cell harvesting, cell disruption, and product isolation. The vertical dotted lines at 5 and 15 g/L represent the change in optimal separation network design