Table 1.

Characteristics of study subjects

	Neurotypical	Angelman
Total patients	72	28
Age (years)	7.0 ± 0.2	5.8 ± 0.3
Male	42 (58%)	14 (50%)
Female	30 (42%)	14 (50%)
Molecular diagnosis	N/A	Class 1 deletion: 7 Class 2 deletion: 10 UBE3A mutation: 6 Atypical deletion: 2 Uniparental disomy: 1 Imprinting defect: 1 Abnormal DNA methylation, negative for deletion: 1
History of seizures	0 (0%)	26 (93%)
Patients with wake in EEG	54 (75%)	26 (93%)
Age (years)	6.6 ± 0.3	5.8 ± 0.3
Male	30 (56%)	14 (54%)
Female	24 (44%)	12 (46%)
Wakeful EEG length (min)	7.9 ± 1.0	18.2 ± 2.3
Seizures under control at time of first recording or no seizure history	54 (100%)	24 (92%)
Patients with sleep in EEG	54 (75%)	13 (46%)
Age (years)	7.1 ± 0.3	6.0 ± 0.4
Male	32 (59%)	8 (62%)
Female	22 (41%)	5 (38%)
Sleep EEG length (min)	13.6 ± 0.8	22.0 ± 2.4
Seizures under control at time of first recording or no seizure history	54 (100%)	12 (92%)