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. 2017 May 8;19:87. doi: 10.1186/s13075-017-1300-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Fluorescence optical imaging (FOI) staining in a patient with diffuse cutaneous systemic sclerosis. Upper left image: strong initial enhancement (IE) in digit II of the right hand just below the fingertip (region 1). Lower left image: IE in the digit III of the left hand near the metacarpophalangeal (MCP) joint (region 6). Upper right image: maximum distal distribution (MDD) in the fingertip (region 0) of digit II of the right hand. Lower right image: MDD in digit V of both hands with the most distal sufficient signal in region 5 of the left digit V and region 1 of the right hand’s digit V. ICG indocyanine green