Table 4.

Recurrence rates^* after MMS and conventional surgery for primary tumors

Thickness	MMS n/N (%)	Conventional n/N (%)ŧ	P value
MIS	4/863 (0.5)	16/81 (20.0) 30	<0.001
		2/22 (9.0) 31	<0.0001
		2/23 (9.0) 32	<0.0001
Invasive	7/556 (1.3)	95/3445 (2.8) 33	0.039
		25/593 (4.2) 34	0.003
		48/638 (7.5) 35	< 0.0001

^*Includes satellite metastasis. Mean follow-up= 3.71 years; Mean time to recurrence= 3.15yrs (SD= 2.41yrs)

^ŧAny tumor growth that re-appeared in the scar, under the skin graft, or within 3cm of the margins of the wide excision. Mean follow-up= 3.5 years ³⁰, 3.2 years ³¹, 3 years ³², 8 years ³³, 3 years ³⁴, 5 years ³⁵

MIS, Melanoma in situ