Table 1.
Patient demographics and comorbidities by severity of psoriasis
| Baseline characteristics in year 2010 | Total | Moderate to severe | Mild | p value |
| (N = 56,406; 100%) | (N = 13,698; 24.3%) | (N = 42,708; 75.7%) | ||
| Age (years), mean (SD) | 51.63 (14.59) | 51.79 (13.95) | 51.58 (14.79) | <0.0001 |
| Male, n (%) | 28,208 (50.01) | 6717 (49.04) | 21,491 (50.32) | 0.0089 |
| Female (%) | 28,198 (49.99) | 6981 (50.96) | 21,217 (49.68) | |
| Region | ||||
| North East | 10,485 (18.59) | 2478 (18.09) | 8007 (18.75) | 0.3327 |
| North Central | 16,528 (29.30) | 3988 (29.11) | 12,540 (29.36) | |
| South | 20,633 (36.58) | 5076 (37.06) | 15,557 (36.43) | |
| West | 8660 (15.35) | 2129 (15.54) | 6531 (15.29) | |
| Missing | 100 (0.18) | 27 (0.20) | 73 (0.17) | |
| Charlson Comorbidity Index, mean (SD) | 0.38 (0.93) | |||
| Comorbidities, n (%) | Total | Moderate to severe | Mild | p value |
| (n = 56,406) | (n = 13,698; 24.3%) | (n = 42,708; 75.7%) | ||
| Psoriatic arthritis | 5557 (9.85) | 2901 (21.18) | 2656 (6.22) | <0.0001 |
| Cardiovascular disease | 9992 (17.71) | 2390 (17.45) | 7602 (17.80) | 0.3476 |
| Depression | 4388 (7.78) | 1161 (8.48) | 3227 (7.56) | 0.0005 |
| Anxiety | 3148 (5.58) | 734 (5.36) | 2414 (5.65) | 0.1923 |
| Diabetes | 8031 (14.24) | 2181 (15.92) | 5850 (13.70) | <0.0001 |
| Hyperlipidemia | 18,911 (33.53) | 4572 (33.38) | 14,339 (33.57) | 0.6703 |
| Hypertension | 19,365 (34.33) | 4775 (34.86) | 14,590 (34.16) | 0.1350 |
| Obesity | 2755 (4.88) | 709 (5.18) | 2046 (4.79) | 0.0687 |
| Cerebrovascular disease | 2122 (3.76) | 462 (3.37) | 1660 (3.89) | 0.0059 |
| Peripheral vascular disease | 2032 (3.60) | 457 (3.34) | 1575 (3.69) | 0.0547 |
| Any of the above comorbiditiesa | 35,644 (63.19) | 9294 (67.85) | 26,350 (61.70) | <0.0001 |
aAny of the above comorbidities means if patients have any of the either comorbidities mentioned above. The percentages do not add up as they are not mutually exclusive