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. 2017 Feb 13;14(5):412–422. doi: 10.1038/cmi.2016.70

Table 1. The physiological and pathological roles of Regnase-1.

Category of biological process Name of biological process Role of Regnase-1 References
  T-cell activation Inhibiting T-cell activation 28, 52, 97, 98
  Monocyte activation Inhibiting monocytes activation 34, 93
  Apoptosis Promoting apoptosis 22, 32, 49, 56, 89, 101
Physiology Cell differentiation Promoting cell differentiation 85
  Angiogenesis Enhancing angiogenesis 83, 84
  Adipogenesis Promoting or inhibiting adipogenesis 86, 87, 88
  Autoimmune gastritis Preventing autoimmune gastritis 72
  Rheumatoid arthritis Promoting rheumatoid arthritis 96
  Myasthenia gravis Unknown 94
  Infections Inhibiting viral infections 31, 36, 37, 91
Pathology Psoriasis Unknown 39, 95
  Silicosis Promoting silicosis 47
  Atherogenesis Promoting atherogenesis 75
  Ischemia Promoting the development of ischemia-associated diseases but inhibiting tissue remodeling 22, 35, 76, 77, 78, 79, 80, 81, 82
  Pernicious anemia Preventing anemia 66, 72, 73, 74
  Carcinogenesis Inhibiting carcinogenesis 64, 99, 100, 101