Table 1. DNA replication in reactivated myotubes: role of TK1 and DCTD.
RNAi | CTR | p21p27, CTR | p21p27, TK1 | p21p27, DCTD | Comparison | |
---|---|---|---|---|---|---|
DNA content (% increase >2n) | 0 | 26.6 | 7.6 | 31.5 | ||
P (Kolmogorov–Smirnov) | <0.000001 | NS | p21p27, CTR | |||
Infection | Ad-CTR | Ad-E1A | Ad-E1A | Ad-E1A | Ad-E1A | |
RNAi | — | CTR | TK1 | DCTD | TK1, DCTD | |
DNA content (% increase >2n) | 0 | 43.8 | 27.5 | 36.3 | 16.6 | |
P (Kolmogorov–Smirnov) | <0.000001 | <0.0054 | <0.000001 | Ad-E1A, CTR |
Abbreviation: NS, not significant